THE LSD CRYSTAL DIARIES

Inside the LSD-bound crystal composition, the facet chain of your lid residue L209EL2 varieties extensive hydrophobic contacts with both LSD and bordering residues in TMs III, IV, and V (Figure 4C). In the event the lid moved apart to show the binding pocket in simulation, many of those contacts broke. We thus hypothesized that L209EL2 acts like a